Transcriptional profiling reveals running promotes cerebrovascular remodeling in young but not midlife mice

We report that running at a young age showed ECM-related changes as well as angiogenesis-related pathways. Midlife running did not show this same affect. Young running vs. young sedentary. Midlife running vs midlife sedentary本研究报道，青年时期进行跑步运动可引发与细胞外基质（Extracellular Matrix，ECM）相关的改变，以及与血管生成（Angiogenesis）相关的通路变化。中年时期开展跑步运动则未呈现出相同的效应。青年跑步组 vs 青年久坐组。中年跑步组 vs 中年久坐组。