meta_data

<b>tblhctmeta.csv: Day and source of hematopoietic cell transplant (HCT) for 1,278 patients</b>PatientID: deidentified identifier of patientsTimepointOfTransplant: deidentified day of HCTHCTSource: hematopoietic cell sources for HCT patients (BM_unmodified: bone marrow; PBSC_unmodified: peripheral blood stem cells; TCD: T-cell depleted; cord: cord blood)Disease: disease of patientswbcPatientId, autoFmtPatientId, nejmPatientId: identifiers for the same patients if they were also included in another previous study (wbcPatientId: Schluter, J. et al. 2019. The gut microbiota influences circulatory immune cell dynamics in humans. <i>BioRxiv</i>; autoFmtPatientId: Taur, Y. et al. 2018. Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant. <i>Science Translational Medicine</i> 10(460); nejmPatientId: Peled, J.U. et al. 2020. Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation. <i>New England Journal of Medicine</i>, <i>382</i>(9), pp.822-834.)<br><b>tbldrug.csv: Timing and route of drug administration for 1,279 patients</b>PatientID: deidentified identifier of patientsStartTimepoint: deidentified day when drug administration startedStopTimepoint: deidentified day when drug administration stopped (including the day)Factor: name of the drugCategory: category of the drugRoute: route of drug administration<br>StartDayRelativeToNearestHCT/StopDayRelativeToNearestHCT: start/stop day of the drug administration relative to the nearest day of bone marrow transplant<br><b>tblInfectionsCidPapers.csv: Day of positive blood cultures for 426 patients </b>(include only microbes analyzed in<b> </b>1. Taur, Y., et al. 2012. Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation. <i>Clinical infectious diseases</i>, <i>55</i>(7), pp.905-914; 2. Stoma, I., et al. 2020. Compositional flux within the intestinal microbiota and risk for bloodstream infection with gram-negative bacteria. <i>Clinical Infectious Diseases</i>.)PatientID: deidentified identifier of patientsTimepoint: deidentified day of infectionInfectiousAgent: the bacteria causing infectionsDayRelativeToNearestHCT: day of infection relative to the nearest day of bone marrow transplant<br><b>tblbc.csv: Daily measurements of white blood cells, platelets and red blood cells for 1,278 patients</b>PatientID: deidentified ID of patientsTimepoint: deidentified day of blood cell measurementBloodCellType: immature monocyte cells (ImmatureMonocytes), sezary cells (SezaryCells), variant lymphocyte cells (VariantLymphocytes), immature granulocyte cells (ImmatureGranulocytes), band cells (BandCells), basophil cells (Basophills), blast cells (BlastCells), eosinophil cells (Eosinophils), lymphocyte cells (Lymphocytes), neutrophil cells (Neutrophils), monocyte cells (Monocytes), platelet (Platelets), total white blood cells (WBCtotal), total red blood cells (RBCtotal)Value: blood cell counts<br>Unit: K per uL (1,000 cells/uL) or M per uL (1,000,000 cells/uL)DayRelativeToNearestHCT: day of blood cell measurement relative to the nearest day of bone marrow transplant<br><br><b>tbltemperature.csv: </b>temperatures for 1,249 patientsPatientID: deidentified identifier of patientsTimepoint: deidentified day when patient temperature was measuredMaxTemperature: Maximum temperature (unit: Fahrenheit) recorded on that day for that patientDayRelativeToNearestHCT: day of temperature measurement relative to the nearest day of bone marrow transplant<br><br><b>tblVanA.csv</b>: Results of PCR detection for <i>vanA </i>gene for 7,547 samplesSampleID: stool sample identifier VanA: whether <i>vanA</i> gene is detected in the sample<b>tblhctmeta.csv：1278例患者造血细胞移植（hematopoietic cell transplant, HCT）的时间与供源</b><br>PatientID：去标识化患者标识符<br>TimepointOfTransplant：造血细胞移植的去标识化天数<br>HCTSource：造血细胞移植患者的造血细胞来源（BM_unmodified：骨髓（bone marrow）；PBSC_unmodified：外周血干细胞（peripheral blood stem cells）；TCD：T细胞清除（T-cell depleted）；cord：脐带血（cord blood））<br>Disease：患者所患疾病<br>wbcPatientId、autoFmtPatientId、nejmPatientId：若患者同时纳入既往另一项研究，则为该患者的对应标识符（wbcPatientId 对应 Schluter J等，2019年，《The gut microbiota influences circulatory immune cell dynamics in humans》，<i>BioRxiv</i>；autoFmtPatientId 对应 Taur Y等，2018年，《Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant》，<i>Science Translational Medicine</i> 10(460)；nejmPatientId 对应 Peled JU等，2020年，《Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation》，<i>New England Journal of Medicine</i> <i>382</i>(9):822-834）<br><br><b>tbldrug.csv：1279例患者给药的时间与途径</b><br>PatientID：去标识化患者标识符<br>StartTimepoint：给药开始的去标识化天数<br>StopTimepoint：给药结束的去标识化天数（含当日）<br>Factor：药物名称<br>Category：药物类别<br>Route：给药途径<br>StartDayRelativeToNearestHCT/StopDayRelativeToNearestHCT：给药开始/结束天数，以最近一次骨髓移植日为参照基准<br><br><b>tblInfectionsCidPapers.csv：426例患者血培养阳性天数</b><br>（仅纳入以下两项研究中分析过的微生物：1. Taur Y等，2012年，《Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation》，<i>Clinical Infectious Diseases</i> <i>55</i>(7):905-914；2. Stoma I等，2020年，《Compositional flux within the intestinal microbiota and risk for bloodstream infection with gram-negative bacteria》，<i>Clinical Infectious Diseases</i>）<br>PatientID：去标识化患者标识符<br>Timepoint：感染发生的去标识化天数<br>InfectiousAgent：引发感染的病原体细菌<br>DayRelativeToNearestHCT：感染发生天数，以最近一次骨髓移植日为参照基准<br><br><b>tblbc.csv：1278例患者白细胞、血小板与红细胞每日检测数据</b><br>PatientID：去标识化患者标识符<br>Timepoint：血细胞检测的去标识化天数<br>BloodCellType：未成熟单核细胞（ImmatureMonocytes）、塞扎里细胞（SezaryCells）、异型淋巴细胞（VariantLymphocytes）、未成熟粒细胞（ImmatureGranulocytes）、杆状核粒细胞（BandCells）、嗜碱性粒细胞（Basophills）、原始细胞（BlastCells）、嗜酸性粒细胞（Eosinophils）、淋巴细胞（Lymphocytes）、中性粒细胞（Neutrophils）、单核细胞（Monocytes）、血小板（Platelets）、白细胞总数（WBCtotal）、红细胞总数（RBCtotal）<br>Value：血细胞计数结果<br>Unit：每微升千个（K per uL，即1000个细胞/微升）或每微升百万个（M per uL，即1000000个细胞/微升）<br>DayRelativeToNearestHCT：血细胞检测天数，以最近一次骨髓移植日为参照基准<br><br><b>tbltemperature.csv：1249例患者体温数据</b><br>PatientID：去标识化患者标识符<br>Timepoint：患者体温检测的去标识化天数<br>MaxTemperature：该患者当日记录的最高体温（单位：华氏度）<br>DayRelativeToNearestHCT：体温检测天数，以最近一次骨髓移植日为参照基准<br><br><b>tblVanA.csv：7547份样本的<i>vanA</i>基因PCR检测结果</b><br>SampleID：粪便样本标识符<br>VanA：样本中是否检测到<i>vanA</i>基因