YTHDC1 promotes stemness maintenance and malignant progression in head and neck squamous cell carcinoma. YTHDC1 promotes stemness maintenance and malignant progression in head and neck squamous cell carcinoma

RNA sequencing was used to detect differential expressed genes (DEGs) between SCC9-sphere and SCC9 cell line and to uncover molecular pathways and target molecules associated with cancer stem cells. Overall design: We then performed gene expression profiling analysis using data obtained from RNA-seq of two biological replicates of the SCC9 cell line and SCC9 sphere for RNA-sequencing profiling.