Impact of diuretic use and simplified Pulmonary Embolism Severity Index on serum sodium predicting all-cause mortality post-discharge following acute PE.^*

*Unless otherwise indicated, data are presented as adjusted hazard ratio (95% confidence interval). Only univariate variables with p<0.10 were included in the multivariate analysis. Only post-discharge analysis was performed as diuretic use on presentation was a significant univariate predictor for only post-discharge death and not for in-hospital death. Multivariate model 1 was adjusted for age (per 1-year), Charlson Comorbidity Index score (per 1-score), whether patient had atrial fibrillation and/or flutter, current smoker status, the estimated glomerular filtration rate (eGFR, per 1 ml/min/1.73 m2) and serum hemoglobin level on admission (per 1 g/L). Model 2 added diuretic use on presentation. Model 3 was adjusted for the simplified Pulmonary Embolism Severity Index (incorporates age, history of malignancy, cardiac failure or chronic pulmonary disease, heart rate ≥110 beats/minute, systolic blood pressure <100 mmHg and arterial oxyhemoglobin <90% at admission), atrial fibrillation and/or flutter, current smoker status, eGFR, serum hemoglobin level and diuretic use.