ChIP-seq of cholangiocytes treated with TGFbeta
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145250
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资源简介：
TGF beta has profound effects on global gene expression changes. To understand the epigenetic mechanisms associated with TGF beta stimulation, we performed ChIP-seq of cholangiocytes to understand the changes in histone modifications associated with TGF beta. We choose H3K27ac and H3K9ac, histone modification associated with gene expression. These histone modifications were correlated with SMAD3 occupancy, which is a canonical downstream mediator of TGF beta signaling. Cholangiocyte cell line, H69, were treated with Vehicle or TGF beta for 16 hours to evaluate H3K27ac, H3K9ac and SMAD3 chromatin occupancy following TGF beta.
创建时间：
2020-02-23
