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Genetic alteration in inflammatory myofibroblastic tumor

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NIAID Data Ecosystem2026-03-14 收录
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Most IMTs with ALK fusion at other organs involve ALK exon 20, whereas ALK fusion involving exon 18 or 19 has been reported only in genitourinary IMTs with a gene fusion partner FN1. With review of the clinicopathological characteristics of such cases, we suggest that the presence of FN1-ALK fusions with ALK exon 18 or 19 rearrangements may be specific to a subset of IMTs arising in the urinary bladder.

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2023-02-15
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