Crystal structure of neutralizing human monoclonal antibody 75C8 in complex with AMA1 DI-DII

Crystal structure of neutralizing human monoclonal antibody 75C8 in complex with AMA1 DI-DII Descriptor: 75C8 Fab Heavy Chain, 75C8 Fab Light Chain, Apical membrane antigen 1 Authors: Patel, P.N, Tang, W.K, Tolia, N.H. Deposit date: 2024-04-25 Release date: 2025-03-12 Last modified: 2025-04-02 Method: X-RAY DIFFRACTION (2.8 Å) Cite: A strain-transcending anti-AMA1 human monoclonal antibody neutralizes malaria parasites independent of direct RON2L receptor blockade. Cell Rep Med, 6, 2025