Crystal structure of compound 1 bound to human Nicotinamide N-methyltransferase

Crystal structure of compound 1 bound to human Nicotinamide N-methyltransferase Descriptor: (3~{S})-1-(2-pyridin-2-ylethyl)-~{N}-(1,3-thiazol-2-yl)piperidine-3-carboxamide, Nicotinamide N-methyltransferase Authors: Yoshida, S, Kondo, N, Uehara, S, Yoshimura, N, Sako, Y, Yamamoto, S, Kitade, M, Tachibana, Y. Deposit date: 2025-12-15 Release date: 2026-03-11 Last modified: 2026-04-29 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Structure-Based Drug Discovery of Non-SAM-Mimetic Bisubstrate Inhibitors against Nicotinamide N ‐Methyltransferase. Acs Med.Chem.Lett., 17, 2026