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Additional file 2 of Proteomics reveals dynamic metabolic changes in human hematopoietic stem progenitor cells from fetal to adulthood

NIAID Data Ecosystem2026-05-02 收录

造血祖细胞发育

蛋白质组学代谢动态

数据链接：

https://figshare.com/articles/dataset/Additional_file_2_of_Proteomics_reveals_dynamic_metabolic_changes_in_human_hematopoietic_stem_progenitor_cells_from_fetal_to_adulthood/27022755 数据链接链接失效反馈

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资源简介：

Additional file2

应用场景：

创建时间：

2024-09-15

造血祖细胞发育

白血病发病机制

Germline mutations in ETV6 are associated with a syndrome of thrombocytopenia and leukemia predisposition, and ETV6 is among the most commonly mutated genes in leukemias, especially childhood B cell a

NIAID Data Ecosystem40

Gene expression profile at single cell level of fixed CD55+ myeloid progenitors

单细胞转录组学

造血祖细胞发育

Murine bone marrow CD55+ myeloid progenitors were fixed and submitted to Flex ScRNA-seq with CITE-seq in order to investigate eosinophil ontogeny and development. Overall design: Murine bone marrow pr

NIAID Data Ecosystem30

The T-box Transcription Factor Eomesodermin Governs Hemogenic Competence of Yolk Sac Mesodermal Progenitors [RNA-Seq]

造血祖细胞发育

转录因子调控

Extra-embryonic mesoderm (ExM), the earliest cells that traverse through the primitive streak, give rise to the endothelium as well as hematopoietic progenitors in the developing yolk-sac (YS). How a

NIAID Data Ecosystem10

SKIDA1 transiently sustains MLL::ENL-Expressing hematopoietic progenitors during neonatal stages and promotes B-lineage priming [scRNA-Seq]

造血祖细胞发育

白血病基因调控

To assess changes in transcriptional responses to Skida1 deletion in the context of MLL::ENL, we performed CITE-seq on Tet-Off-ME mice. Overall design: We sorted Lineage-KIT+ progenitors from P0 liver

NIAID Data Ecosystem30

Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.

造血祖细胞发育

Flt3-ITD突变抗性

Gene expression in control and Flt3-ITD, Stat5 and Runx1 mutant HSCs and HPCs from different developmental stages. HSCs and HPCs were isolated from wild type and FLT3-ITD/+ mice at the indicated ages,

NIAID Data Ecosystem30

Additional file 2 of Proteomics reveals dynamic metabolic changes in human hematopoietic stem progenitor cells from fetal to adulthood

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