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Identification and Characterization of a Novel Competence Gene, comC, Required for DNA Binding and Uptake in Acinetobacter sp. Strain BD413

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PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC107065/
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A gene (comC) essential for natural transformation was identified in Acinetobacter sp. strain BD413. ComC has a typical leader sequence and is similar to different type IV pilus assembly factors. A comC mutant (T308) is not able to bind or take up DNA but exhibits a piliation phenotype indistinguishable from the transformation wild type as revealed by electron microscopy.
提供机构:
American Society for Microbiology (ASM)
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