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Genes of CRISPR-Cas9 negative screening.

Figshare2026-02-09 更新2026-04-28 收录

CRISPRi筛选

免疫细胞互作网络

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https://figshare.com/articles/dataset/_p_Genes_of_CRISPR-Cas9_negative_screening_p_/31299722 数据链接链接失效反馈

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We compared changes in sgRNA abundance between T24 cells challenged and unchallenged by CD8+ T cells, and then performed negative screening (p 2Fold change (XLSX)

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创建时间：

2026-02-09

抗体生产优化

CRISPRi筛选

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Genome-scale CRISPRi Perturb-seq on both unstimulated and stimulated Jurkat cells reveals regulators of human T-cell signaling

T细胞信号传导调控

CRISPRi筛选

The goal of the experiment is to identify genes involved in T-cell receptor (TCR) signaling and T-cell activation in human T cells. The Jurkat E6 cell line, engineered to express dCas9-KRAB and transd

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Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.

干细胞鉴定

CRISPRi筛选

Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,

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Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Human cortical organoids with engineered microglia-like cells [CROP-seq]

神经退行性疾病模型构建

CRISPRi筛选

Microglia play vital roles in the emergence and preservation of a healthy brain microenvironment with their impaired functions highlighted in neurodevelopmental and neurodegenerative disorders. Howeve

NIAID Data Ecosystem20

Genes of CRISPR-Cas9 negative screening.

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