HLA-I binding affinity of eluted peptides derived from the invariant chain.
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*See Figure 2 for amino acid position in the invariant chain protein.†IC50 is the concentration used to obtain half maximal competition and represents the mean value of two independent experiments.‡Binding affinity is classified according to the following IC50 cut-off values: high affinity, ≤5 µM; intermediate (int) affinity, 5–15 µM; low affinity, 15–100 µM; no binding, >100 µM [21].
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2015-12-02



