Crystal structure of human monoacylglycerol lipase in complex with compound 2d
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Crystal structure of human monoacylglycerol lipase in complex with compound 2d Descriptor: (2s,4R)-2-{4-[(2-chloro-4-fluorophenoxy)methyl]piperidine-1-carbonyl}-7-oxa-5-azaspiro[3.4]octan-6-one, Monoglyceride lipase Authors: Qin, L, Gay, S.C, Lane, W, Skene, R.J. Deposit date: 2020-12-21 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2 H -benzo[ b ][1,4]oxazin-6-yl Moiety. J.Med.Chem., 64, 2021
创建时间：
2020-12-21
