Effect of antidepressant medication use during pregnancy on preterm birth: meta-analysis results.

(1)Typically 1st trimester; some women continued during pregnancy, others discontinued.(2)Typically 3rd trimester.(3)Factors varied between studies, but typically included maternal age, smoking, alcohol use, parity, and history of prematurity or miscarriage.(4)Values of I2 are percentages (% of variance explained). 95% uncertainty intervals are calculated as proposed by Higgins and Thompson [89].