Relationship between experimental ΔΔG, Δlog10(koff), Δlog10(kon) and change in interface hotspot energy (Int_HS_Energy) for 713 mutations in SKEMPI.
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(A) Shows PCC between experimental ΔΔG with the respective Δlog10(koff) and Δlog10(kon) for single-point alanine, single-point non-alanine, multi-point and all 713 mutations. (B) Shows PCC between Int_HS_Energy with the respective ΔΔG, Δlog10(koff) and Δlog10(kon) for single-point alanine, single-point non-alanine, multi-point and all 713 mutations. Experimental values for the 713 mutations used here are extracted from SKEMPI [41] and are presented in Dataset S1.
创建时间：
2015-12-02
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