Cryo-EM structure of GPR119-Gs-Nb35 complex with small molecule agonist MBX-2982

Cryo-EM structure of GPR119-Gs-Nb35 complex with small molecule agonist MBX-2982 Descriptor: 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(1,2,3,4-tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Kim, D.-G, Cherezov, V. Deposit date: 2024-01-01 Release date: 2024-10-30 Last modified: 2025-03-05 Method: ELECTRON MICROSCOPY (3.51 Å) Cite: Native mass spectrometry prescreening of G protein-coupled receptor complexes for cryo-EM structure determination. Structure, 32, 2024