FOXC1 gene variations identified in dominant glaucoma cases and associated clinical features.

1The variants were present in the heterozygous state; 2Number of drugs and/or surgery; 3Novel variants; AOG/ARA/JOAG/LCG/PCG: Adult-onset glaucoma/Axenfeld-Rieger anomaly/juvenile-onset glaucoma/late-onset primary congenital glaucoma/primary congenital glaucoma; B: bilateral; C/D: cup/disk ratio; NA: Not available; OD/OS: right eye/left eye. Mutations were named according to RefSeq: NM_001453.2 and using directions from Mutalyzer (https://humgenprojects.lumc.nl/trac/mutalyzer). FOXC1 gene variations identified in dominant glaucoma cases and associated clinical features.