MYC is dysregulated in most human cancers and is a DNA damage response (DDR) modulator capable of both promoting genomic instability and enhancing DNA repair. Here, we show that Omomyc, the first dire
Exosomes endogenous microRNAs (miRNAs) play critical roles in many biological processes.to obtain profiles of the miRNAs of exosomal and cell lysates in ovarian cancer cell lines. Overall design: We u
PARP inhibition has been approved as a compelling strategy for treating multiple human cancers bearing homologous recombination defects (HRD). However, due to the lack of functional biomarkers of PARP
The data of Bittner and Anglesio Ovarian Cancer from oncomine database used in the article "Establishment of highly metastatic ovarian cancer model with omental tropism via in vivo selection"