End-stage liver diseases are an increasing health burden and liver transplantations are currently the only curative treatment option. Due to a lack of donor livers, alternative treatments are urgently
Embryoid bodies (EBs) and self-organizing organoids derived from human pluripotent stem cells (hPSC) recapitulate tissue development in a dish and hold great promise for disease modeling and drug deve
Differentiated HB-orgs and P-heporgs from hESCs were cultured under static and dynamic conditions, RNAseq was performed to compare the differences. Overall design: HB-orgs and P-heporgs were cultured
We established a platform for the brain organoid culture by using human decellularized brain extracellular matrix (BEM) and a microfluidic device. This engineering concept of reconstituting brain-mim
Organoids are a reliable experimental model for mimicking the cellular characteristics and architectural types of tissues or organs in vitro. Ruminants are important economic animals. The rumen is the
