ENDOMETRIOSIS: ETIOPATHOGENESIS, EPIDEMIOLOGY, DIAGNOSIS AND THE CURRENT STATE OF TREATMENT (LITERATURE REVIEW AND STATISTICAL ANALYSIS)

This article provides a systematic review and statistical analysis of contemporary scientific data on endometriosis, covering its epidemiology, etiopathogenetic theories, diagnostic approaches and treatment strategies. Statistical evidence from the Global Burden of Disease (GBD) studies, meta-analyses and major clinical trials is synthesized. Endometriosis affects approximately 10% of women of reproductive age, with a mean diagnostic delay of 6.6–9.7 years, and infertility observed in 30–40% of patients. The efficacy and limitations of hormonal therapy (progestins, GnRH agonists and antagonists), surgery and assisted reproductive technologies are compared. The detrimental impact of the disease on quality of life and the economy is substantiated by statistical data.