Structure of the A467T mutant of human mitochondrial DNA polymerase gamma in complex with PZL-A

Structure of the A467T mutant of human mitochondrial DNA polymerase gamma in complex with PZL-A Descriptor: 1-[(4S)-8-chloranyl-3,4-dihydro-2H-chromen-4-yl]-3-(1-phenylpyrazol-3-yl)urea, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ... Authors: Valenzuela, S, Falkenberg, M. Deposit date: 2024-08-13 Release date: 2025-04-16 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: Small molecules restore mutant mitochondrial DNA polymerase activity. Nature, 642, 2025