Intrapleural pressure during a forced vital capacity (VC) manoeuvre is often in excess of that required to generate maximal expiratory airflow. This excess pressure compresses alveolar gas (i.e., thor
The GAMLSS model was used with a gamma distribution for all outcomes except DL,NO/DL,CO,5s which had a normal distribution, and DL,CO,5s,hb-corr that had a Box-Cox-Cole-Green distribution (BCCG). H =
Respiratory frequency (f) and tidal volume (VT) were measured using spontaneously breathing rats. Fiber activity was measured using ventilator-assisted rats. Baseline values were averaged over 10 brea