Data from: A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection
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https://datadryad.org/dataset/doi:10.5061/dryad.gn95r
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资源简介:
Asymptomatic ebolavirus infection could greatly influence transmission
dynamics, but there is little consensus on how frequently it occurs or
even if it exists. This paper summarises the available evidence on
seroprevalence of Ebola, Sudan and Bundibugyo virus IgG in people without
known ebolavirus disease. Through systematic review, we identified 51
studies with seroprevalence results in sera collected from 1961 to 2016.
We tabulated findings by study population, contact, assay, antigen and
positivity threshold used, and present seroprevalence point estimates and
95% confidence intervals. We classified sampled populations in three
groups: those with household or known case-contact; those living in
outbreak or epidemic areas but without reported case-contact; and those
living in areas with no recorded cases of ebolavirus disease. We performed
meta-analysis only in the known case-contact group since this is the only
group with comparable exposures between studies. Eight contact studies
fitted our inclusion criteria, giving an overall estimate of
seroprevalence in contacts with no reported symptoms of 3.3% (95% CI
2.4-4.4, p<0.001), but with substantial heterogeneity.
提供机构:
Dryad
创建时间:
2016-12-15



