Datasets and Rscripts for : Multiomic Dissection of Movement and Neurocognitive Toxicity Following BCMA-Targeting CAR T Cell Therapy
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https://zenodo.org/doi/10.5281/zenodo.15792201
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Displayed are two R objects:The first object contains all cells recovered from cerebrospinal fluid (CSF) and peripheral blood (PBMCs) via single-cell RNA seqeuncing and TCR-sequencing of a patient with parkinsonism following CAR T cell therapy. The second object represents a subset of these data, specifically containing T cells identified from the combined CSF and PBMC samples.
Additionally, two R scripts are provided:
One script details the quality control, normalization, and integration steps performed on the datasets.
The other script includes the code used to generate the plots for downstream analysis and visualization.
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2025-07-09



