Promoter proximal pausing and its regulation by c-Myc in embryonic stem cells
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2019-05-15
相关数据集
CBP regulates promoter-proximal RNA polymerase II. Drosophila melanogaster
Transcription activation involves RNA polymerase II (Pol II) recruitment and release from the promoter into productive elongation, but how specific chromatin regulators control these steps is not full
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NELF regulates a promoter-proximal step distinct from RNA Pol II pause-release. NELF regulates a promoter-proximal step distinct from RNA Pol II pause-release
RNA polymerase II (Pol II) is generally paused at promoter-proximal regions in most metazoans, and based on in vitro studies, this function has been attributed to the negative elongation factor (NELF)
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Promoter-Proximal Pausing on the hsp70 Promoter in Drosophila melanogaster Depends on the Upstream Regulator
RNA polymerase II pauses in the promoter-proximal region of many genes during transcription. In the case of the hsp70 promoter from Drosophila melanogaster, this pause is long-lived and occurs even wh
PubMed Central20
SPT5 stabilizes promoter-proximal RNA polymerase II prior to release into gene bodies. SPT5 stabilizes promoter-proximal RNA polymerase II prior to release into gene bodies
The regulation of gene expression by RNA polymerase II (Pol II) is a multistep process requiring the concerted action of diverse transcription factors. Very little is known about in vivo function of t
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Control of RNA polymerase II promoter-proximal pausing by DNA supercoiling [ChIP-seq]
During transcription, DNA supercoiling generated by the advance of RNA polymerase II (Pol II) is resolved by DNA topoisomerases, enzymes that bind chromatin and produce transient breaks to relax DNA.
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