Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition

ChEBI2013-07-09 更新2026-07-21 收录

神经细胞表观遗传学

组蛋白去乙酰化酶抑制剂

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Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition

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2013-07-09

Dnmt1 deletion in PV-positive cortical interneurons of 6 month and 18 month old mice. Dnmt1 deletion in PV-positive cortical interneurons of 6 month and 18 month old mice

神经细胞表观遗传学

年龄相关甲基化

The emerging role of epigenetic mechanisms like DNA methylation executed by DNA methyltransferases (DNMTs) in synaptic function irrevocably raises the question for the targeted subcellular processes a

NIAID Data Ecosystem110

X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition. X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition

神经肌肉疾病治疗

组蛋白去乙酰化酶抑制剂

X-linked myotubular myopathy (XLMTM) is a fatal neuromuscular disorder caused by loss of function mutations in MTM1 . At present, there are no directed therapies for XLMTM, and incomplete understandin

NIAID Data Ecosystem50

Allele-specific H3K27me3, H3K27ac and Ctcf ChIP-seq in Smchd1 control and Smchd1 deleted female neural stem cells. [H3K27me3]

染色体构象调控

神经细胞表观遗传学

We sought to examine whether the non-canonical SMC protein Smchd1 plays a role in chromosome conformation. We used in situ Hi-C to analyse chromosome conformation changes upon deletion of the epigenet

NIAID Data Ecosystem40

GSM8112040_KPNYN_GATA3_1_R1.bigWigNeuroblastoma cell lines

神经细胞表观遗传学

转录因子结合分析

Cut and Run signal tracks from Neuroblastoma cell lines

Figshare2024-05-16 更新60

Table_13_Genome-Wide DNA Methylation and Hydroxymethylation Changes Revealed Epigenetic Regulation of Neuromodulation and Myelination in Yak Hypothalamus.XLSX

神经细胞表观遗传学

高海拔脑适应

Both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are important epigenetic modifications in neurodevelopment. However, there is little research examining the genome-wide patterns of 5mC a

NIAID Data Ecosystem40

Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition

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