Introduction: While progressive MRI brain changes characterize advanced Parkinson's disease (PD), little has been discovered about structural alterations in the earliest phase of the disease, i.e. in
Resulting clusters obtained by whole brain-based spatial statistics (WBSS) of MD, RD, and AD maps from APP mice compared to wt mice (cluster size in pixels).
* Significance after Bonferroni-correction (P Sub-regions 1–7 represent rostrum, genu, rostral body, anterior mid-body, posterior mid-body, isthmus, and splenium of the corpus callosum, respectively.M
