Morphine and clonidine were administered in a dose-ratio of 1∶1 for spinal and 10∶1 for systemic administration; ∼ indicates that the ED50 value was determined by extrapolation (in cases where maximum
Morphine and clonidine were administered in a dose-ratio of 1∶1 for spinal and 10∶1 for systemic administration; ∼ indicates that the ED50 value was determined by extrapolation (in cases where maximum
The biochemical IC50 values for ARQ 092, ARQ 751, MK-2206, and GDC-0068 were determined against full-length active form of AKT1, 2, and 3.ARQ 092 and ARQ 751 potency.
