Immunohistochemical data of castration resistant bone metastases stratified according to expression of AR splice variants (AR-V).

Continuous values are given as median (min–max values). aAR-V high bone metastases were defined to have detectable levels of the AR-V567es transcript and/or the AR-V7 transcript levels in the upper quartile while other CRPC bone metastases had lower AR-V mRNA levels. bAn AR score of 8 or above was defined as high and associated with a particularly short survival after orthopedic surgery [3]. cA PSA score of 8 and below (median and below) was associated with an unfavorable outcome in CRPC patients [3]. *P≤0.05 according to Chi-square test. dPatients with AR-V high bone metastases were not statistically different from other patients with bone metastases regarding any of the clinical characteristics in Table 1.