Transcriptome analysis of six-day-old Neurospora crassa perithecia: sad-1+ versus sad-1(delta)

Meiotic silencing by unpaired DNA (MSUD) is a biological process that detects unpaired genes between homologous chromosomes during meiosis. The RNA-dependent RNA polymerase SAD-1 is required for MSUD. This project seeks to compare the transcriptome of SAD-1+ perithecia (fruiting bodies with meiotic cells) with the transcriptome of SAD-1(delta)-perithecia. The two transcriptomes may also provide insight on the nature of MSUD-associated RNA molecules.