Lycopodium Alkaloids: Lycoplatyrine A, an Unusual Lycodine–Piperidine Adduct from Lycopodium platyrhizoma and the Absolute Configurations of Lycoplanine D and Lycogladine H

Three new Lycopodium alkaloids comprising two lycodine-type alkaloids (1, 2) and one fawcettimine alkaloid (3), in addition to 16 known alkaloids, were isolated from Lycopodium platyrhizoma. The structures of these alkaloids were elucidated based on analysis of their NMR and MS data. Lycoplatyrine A (1) represents an unusual lycodine–piperidine adduct. The structures and absolute configurations of lycoplanine D (hydroxy-des-N-methyl-α-obscurine, 10) and lycogladine H (11) were confirmed by X-ray diffraction analysis.