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Effect sizes for 200+ polygenic scores

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Figshare2021-11-30 更新2026-04-08 收录
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https://figshare.com/articles/dataset/Effect_sizes_for_215_polygenic_scores/14074760/2
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资源简介:
- PGS-effects.csv.gz: vectors of effect sizes for 215 polygenic scores (PGS)- pred-cor: partial correlations of these PGS with the corresponding phenotypes, in eight ancestry groups from the UK Biobank- phenotype-description.xlsx: description of all phenotypes used in the study (30 were discarded due to very low prediction)-&gt; these report the best prediction from penalized regression and LDpred2.<br><br>We also provide these files separately for penalized regression (PLR) and LDpred2-auto (without using the test set).<br>The effect size file for penalized regression is very small because vectors of effects are very sparse.<br><br>Those are based on the UK Biobank data only.<br>
提供机构:
Privé, Florian
创建时间:
2021-11-30
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