Human Protein Atlas - Cell line

The Cell Line section contains information on genome-wide RNA expression profiles of human protein-coding genes in 1055 human cell lines, including 985 cancer cell lines. The transcriptomics analysis includes classification based on specificity analysis across 27 cancer types, distribution and expression cluster analysis across all cell lines and for selected cancer types also analysis of similarity of the cell lines to their corresponding cancer type. More information about the specific content and the generation and analysis of the data in the section can be found in the Methods summary.
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if a gene is enriched in cellines from a particular cancer type (specificity)
which genes have a similar expression profile across the cell lines (expression cluster)
the catalogue of genes elevated in each of the cell lines
which cell line has the most consistent expression profile to its corresponding TCGA disease cohort (i.e., the best cell lines for cancer study)
cancer-related pathway and cytokine activity of each cell line

本数据集的细胞系部分收录了1055个人类细胞系中蛋白质编码基因的全基因组RNA表达谱信息，其中包含985种癌细胞系。转录组学分析涵盖了基于27种癌症类型特异性分析的分类，以及所有细胞系和选定癌症类型的分布与表达聚类分析，此外，对于选定的癌症类型，还进行了细胞系与其相应癌症类型相似性的分析。关于本部分特定内容以及数据的生成与分析的更多信息，可详见方法概要。了解以下内容：
1. 某特定癌症类型细胞系中富集的基因（特异性分析）；
2. 在细胞系中具有相似表达谱的基因（表达聚类分析）；
3. 各细胞系中上调的基因目录；
4. 哪种细胞系与其对应的TCGA疾病队列具有最一致的表达谱（即，最适合癌症研究的最佳细胞系）；
5. 各细胞系的癌症相关通路和细胞因子活性。