CA-4G investigates the impact of different treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing
Differences at end of treatment in alpha diversity and median relative abundance of taxa between subjects who had or did not have a confirmed recurrence of C. difficile during the study.
Probiotics are often consumed after antibiotic treatment to prevent antibiotic-associated diarrheal disease, most commonly caused by C. difficile. However, the impact of probiotic bacteria on the post