Crystal Structures of PIM1 in Complex with Macrocyclic Compound H3
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Crystal Structures of PIM1 in Complex with Macrocyclic Compound H3 Descriptor: 8-Methyl-2,5,20-trioxa-8,13,17-triazatetracyclo[11.10.2.014,19.021,25]pentacosa-1(24),14(19),15,17,21(25),22-hexaene, Serine/threonine-protein kinase pim-1 Authors: Shen, C, Xie, Y, Ren, X, Zhou, Y, Niu, H. Deposit date: 2022-05-15 Release date: 2022-07-13 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.66 Å) Cite: Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3-e][1,4]oxazine derivatives as novel Pim-1 kinase inhibitors. Bioorg.Med.Chem.Lett., 72, 2022
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2022-05-15
