Investigating the potential reduced damage of redox proteins by using low wavelength X-ray diffraction monitored by UV-vis spectroscopy

BM31 offers a unique possibility to investigate the proposed reduced radiation-damage of redox proteins at lower wavelength X-ray diffraction. The overall aim of the project is a proof-of-concept if the use of lower wavelength X-rays can reduced radiation-induced reduction of redox- and metalloproteins, and to see if this can be an alternative to neutron diffraction or XFEL. The second goal will be to obtain the unreduced structures of selected redox proteins. The radiation damage will be monitored with in situ single-crystal spectroscopy which is available at the Swiss-Norwegian Beam Lines.