MM-GBSA calculations of the protein stability for the ABL kinase^*.

*The columns 2–4 represent the protein stability contributions calculated for the Src-like inactive form of ABL for the WT, T3135I and L387M mutants. The columns 5–7 represent the respective protein stability contributions calculated in the active form of ABL for the WT, T315I and L387M mutants. All energies are in Kcal/mol. The contributions of the free energies are defined in the Materials and Methods section.