AU-rich sequence motifs (specifically sequences containing reiterations of AUUUA) are found in the 3' untranslated region of mammalian mRNAs encoding cytokines, adhesion molecules, and protooncogenes.
aEvaluated by densitometry of PAGE Gels Stained with Coomassie Blue R-250 bPurified according to cGMP standards ND = not done WT = wild type CH = codon harmonized
While regulation of the activity of developmental control genes at the transcriptional level as well as by specific miRNA-based degradation are intensively studied, little is known whether general cel
