Methods and compositions for targeted editing of polynucleotides
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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The present invention relates to methods and compositions for modifying a target site in a DNA molecule. The present disclosure provides a DNA-targeting RNA duplex which comprises a crRNA molecule and a tracrRNA molecule and methods of using these molecules for modification of a target DNA. Modifications include targeted transgene insertion, targeted allelic replacement, and targeted mutagenesis.
提供机构:
国家林业和草原科学数据中心
创建时间:
2023-02-12



