BACE1 in complex with a macrocyclic inhibitor
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BACE1 in complex with a macrocyclic inhibitor Descriptor: (E)-N-(2-methylpropylidene)-N~2~-{[(4S)-17-[(methylsulfonyl)(propyl)amino]-2-oxo-3-azatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaen-4-yl]methyl}-D-threoninamide, Beta-secretase 1 Authors: Yen, Y.C, Ghosh, A.K, Mesecar, A.D. Deposit date: 2019-02-04 Release date: 2019-10-09 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.132 Å) Cite: Development of an Efficient Enzyme Production and Structure-Based Discovery Platform for BACE1 Inhibitors. Biochemistry, 58, 2019
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2019-02-04
