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Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

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Zenodo2021-09-17 更新2026-05-25 收录
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Supplementary Data files to accompany manuscript by Harding et al "Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1" Supplementary Data 1 - Multiple sequence alignment for HTT used for Consurf analysis Supplementary Data 2 - Multiple sequence alignment for HAP40 used for Consurf analysis Supplementary Data 3 - Apo HTT cryo-EM map Supplementary Data 4 - HTT-HAP40 Q23 regularised SAXS profile Supplementary Data 5 - HTT-HAP40 Q54 regularised SAXS profile Supplementary Data 6 - HTT-HAP40 Δexon 1 regularised SAXS profile Supplementary Data 7 - XL-MS data Supplementary Data 8 - HTT-HAP40 ensemble weightings Supplementary Data 9 - HTT-HAP40 Q23 ensemble models Supplementary Data 10 - HTT-HAP40 Q54 ensemble models Supplementary Data 11 - HTT-HAP40 Δexon 1 ensemble models

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2021-09-17
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