首页/数据集/DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII. DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII

DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII. DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII

NIAID Data Ecosystem2026-03-09 收录

DNA甲基化转录调控

表观遗传抑制剂

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA259204 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2014-08-22

细胞癌靶向治疗

表观遗传抑制剂

Small-cell lung cancer (SCLC) arises from neuroendocrine cells within the lung. Along with deletion or loss of function Rb and TP53 mutations, which occur in almost all cases, subsets of SCLC are driv

NIAID Data Ecosystem50

Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding

表观遗传抑制剂

受体-配体相互作用

Development of inhibitors for histone methyllysine reader proteins is an active area of research due to the importance of reader protein–methyllysine interactions in transcriptional regulation and dis

Figshare2022-01-11 更新30

Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor

蛋白质结构解析

表观遗传抑制剂

Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor Descriptor: 2-chloro-5-(4-methyl-6-oxo-3-phenylpyrano[2,3-c]pyrazol-1(6H)-yl)benzoic acid, Histone-lysine N-methyltransf

Protein Data Bank Japan2023-10-04 更新20

The histone deacetylase HDAC7 represses lineage-inappropriate genes and is essential for proper B cell generation

B细胞发育

表观遗传抑制剂

B lymphocyte development is a complex process tightly controlled at the transcriptional level by the action of networks of transcription factors. The repression of genes from alternative lineages is n

NIAID Data Ecosystem40

An integrated epigenome and transcriptome analysis to clarify the effect of epigenetic inhibitors in gastrointestinal stromal cells (Expression). An integrated epigenome and transcriptome analysis to clarify the effect of epigenetic inhibitors in gastrointestinal stromal cells (Expression)

胃肠道间质瘤表观遗传

表观遗传抑制剂

Epigenetic alterations play an important role in the pathogenesis of gastrointestinal stromal tumors (GISTs). To obtain better insight into the GIST epigenome, we analyzed genome-wide histone modifica

NIAID Data Ecosystem20

DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII. DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII

资源简介：

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