Organocatalyzed Enantioselective Mannich Reaction of Pyrazoleamides with Isatin-Derived Ketimines
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https://figshare.com/articles/dataset/Organocatalyzed_Enantioselective_Mannich_Reaction_of_Pyrazoleamides_with_Isatin_Derived_Ketimines/2290999
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The first organocatalytic enantioselective Mannich reaction of pyrazoleamides with isatin-derived N-Boc ketimines has been developed to afford 2-oxindole-based chiral β-amino amides in good yields (84–97%) with excellent diastereo- and enantioselectivities (up to 99:1 dr and >99% ee).
创建时间：
2016-02-17
