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Crystal structure of human CYP3A4 bound to the testosterone dimer

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Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Crystal structure of human CYP3A4 bound to the testosterone dimer Descriptor: 17alpha-hydroxy-7alpha-[(2Z)-4-(17beta-hydroxy-3-oxo-8alpha-androst-4-en-7beta-yl)but-2-en-1-yl]-8alpha,10alpha,13alpha,14beta-androst-4-en-3-one, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE Authors: Sevrioukova, I.F. Deposit date: 2021-03-04 Release date: 2021-04-28 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Innovative C 2 -symmetric testosterone and androstenedione dimers: Design, synthesis, biological evaluation on prostate cancer cell lines and binding study to recombinant CYP3A4. Eur.J.Med.Chem., 220, 2021
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2021-03-04
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