Understanding the structure and phytochemical loading of bile salt containing liposomes

The information about the morphology of colloidal systems plays an essential role in controlling the biological fate and bioavailability of cargo loaded systems in the gastrointestinal tract. Recently there has been interest in the incorporation of bile salts (BSs) into phospholipid vesicles to enhance the bioavailability of phytochemicals with the modification of the structure. BSs containing systems are already utilized in the pharmaceutical industry as a delivery vehicles, however, they have not been employed for the encapsulation of phytochemicals in the food industry.Resveratrol (as a model phytochemical) loaded phospholipid/BSs system will be used to investigate structures and interactions, controlling the fate of the system in the gastrointestinal tract, and explore the adaptability of the system into the food formulations.