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Rheumatoid Synovial Subsets of CD3+ T cells defined by PD-1+ and PD-1- Cells Drive Fibroblasts into Distinct Endotypes

ChEBI2025-11-27 更新2026-07-12 收录

类风湿关节炎免疫病理

滑膜细胞互作机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-15969 数据链接链接失效反馈

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Rheumatoid Synovial Subsets of CD3+ T cells defined by PD-1+ and PD-1- Cells Drive Fibroblasts into Distinct Endotypes

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创建时间：

2025-11-27

类风湿关节炎免疫病理

T细胞共刺激通路

BackgroundCurrently, the pathogenesis of rheumatoid arthritis (RA) is not clearly understood. The LIGHT/HVEM/BTLA co-signaling pathway may be involved in the pathogenesis of RA, although reports on th

Figshare2016-11-01 更新60

Interplay of NLRC4/NLRP3 inflammasomes and Fc-ˠ-Receptors on CD1c+ DC Associates with Pathogenic IFNˠ+IL17+ T cells and RA Severity. Interplay of NLRC4/NLRP3 inflammasomes and Fc-ˠ-Receptors on CD1c+ DC Associates with Pathogenic IFNˠ+IL17+ T cells and RA Severity

类风湿关节炎免疫病理

树突状细胞功能

Deregulated myeloid cells infiltrating to the joints likely contribute to rheumatoid arthritis (RA) pathogenesis through multiple mechanisms, including the secretion of proinflammatory cytokines and t

NIAID Data Ecosystem30

Cytokine, activation marker, and chemokine receptor expression by individual CD4(+) memory T cells in rheumatoid arthritis synovium

类风湿关节炎免疫病理

单细胞分析

INTRODUCTION: In RA large numbers of CD4(+) memory T cells infiltrate the inflamed synovium [1,2,3]. The accumulated CD4(+) memory T cells in the RA synovium appear to be activated, because they expre

PubMed Central2000-07-03 更新20

Table_1.docx

类风湿关节炎免疫病理

细胞功能分析

Natural antibodies, particularly natural IgM, are proved to play indispensable roles in the immune defenses against common infections. More recently, the protective roles of these natural IgM were als

NIAID Data Ecosystem30

Table1_Dysfunctions, Molecular Mechanisms, and Therapeutic Strategies of Regulatory T Cells in Rheumatoid Arthritis.docx

类风湿关节炎免疫病理

调节性T细胞治疗

Regulatory T cells (Tregs) represent a distinct subpopulation of CD4+ T lymphocytes that promote immune tolerance and maintain immune system homeostasis. The dysfunction of Tregs is tightly associated

NIAID Data Ecosystem30

Rheumatoid Synovial Subsets of CD3+ T cells defined by PD-1+ and PD-1- Cells Drive Fibroblasts into Distinct Endotypes

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