In this paper, the performance of hurdle models in rare events data is improved by modifying their binary component. The rare-event weighted logistic regression model is adopted in place of logistic r
TEER was measured at the end of the experiment. Deviation (dev) is calculated as the absolute value of the difference between the two experiments divided by 2. The number n is the number of independen
L'étude d'absorption cutanée in vivo présentée dans cette Ligne directrice fournit des éléments nécessaires pour extrapoler des études orales lors d’évaluations de sécurité après une exposition cutané
Organisation for Economic Co-operation and Development40
For microsomal stability, verapamil was used as a high-metabolism control (0.24% remaining with NADPH) and warfarin was a low-metabolism control (85% remaining with NADPH). The kinetic solubility limi
