Nuclear Speckles (NS) are phase-separated condensates of protein and RNA whose components dynamically coordinate RNA transcription, splicing, transport and DNA repair. NS, probed largely by imaging st
Nucleus, chromatin, and chromosome organization studies heavily rely on fluorescence microscopy imaging to elucidate the distribution and abundance of structural and regulatory components. Three-dimen
Features are computed from a digitized image of a fine needle aspirate (FNA) of a breast mass. They describe characteristics of the cell nuclei present in the image. n the 3-dimensional space is that
Analysis of X chromosome localization within the nucleus via the three-zone assay. Statistical analysis was done using Student’s t-tests. Statistically significant differences (p<0.05) are highlighted