EED in complex with PRC2 allosteric inhibitor compound 8
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EED in complex with PRC2 allosteric inhibitor compound 8 Descriptor: 5-(furan-2-ylmethylamino)-[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED Authors: Zhao, K, Zhao, M, Luo, X, Zhang, H. Deposit date: 2016-10-14 Release date: 2017-01-25 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy J. Med. Chem., 60, 2017
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2016-10-14
