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Novel, potent small molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design

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Protein Data Bank Japan2023-12-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2bt0
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Novel, potent small molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design Descriptor: 4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP90-ALPHA Authors: Dymock, B.W, Barril, X, Brough, P.A, Cansfield, J.E, Massey, A, McDonald, E, Hubbard, R.E, Surgenor, A, Roughley, S.D, Webb, P, Workman, P, Wright, L, Drysdale, M.J. Deposit date: 2005-05-24 Release date: 2005-06-02 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design. J. Med. Chem., 48, 2005
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2005-05-24
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